Solgar Folate Metafolin 400µg vs Jarrow Formulas Methyl Folate
Side-by-side comparison of scores, ingredients, prices and real customer feedback for Solgar Folate Metafolin 400µg and Jarrow Formulas Methyl Folate.
Last verified: 28 Mar 2026 · Based on 108 reviews
Our Verdict: Solgar Folate Metafolin 400µg or Jarrow Formulas Methyl Folate?
Solgar edges ahead with a marginally higher ingredient quality score (93 vs 91) and a lower price, making it the better buy for most. Jarrow is the smarter pick for strict vegans or those wanting better value per tablet with its 60-capsule pack.
— AIScored Editorial Team
Solgar Folate Metafolin 400µg scores 86.0/100 vs Jarrow Formulas Methyl Folate at 81.0/100. Solgar Folate Metafolin 400µg wins on effectiveness, ingredient quality, side effects. Jarrow Formulas Methyl Folate is stronger on value for money.
Solgar Folate Metafolin 400µg vs Jarrow Formulas Methyl Folate: What Does the Data Say?
Solgar Folate (As Metafolin®) 400µg uses a bioactive form of B9 that your body can use immediately. It scores 88/100 for effectiveness because it bypasses the conversion steps needed for standard folic acid. This makes it a top pick for people with the MTHFR mutation. Jarrow Formulas Vegan Methyl Folate, 400 mcg uses Quatrefolic instead. While both products provide 400µg per serving, Solgar Folate (As Metafolin®) 400µg leads on ingredient quality with a score of 93/100. Jarrow Formulas Vegan Methyl Folate, 400 mcg follows closely at 90/100.
If you are planning a pregnancy or have a diagnosed deficiency, Solgar Folate (As Metafolin®) 400µg is the superior option with an overall score of 86/100. However, it costs £9.20 for only 50 tablets. This small pack size hurts its value score, which sits at 68/100. Jarrow Formulas Vegan Methyl Folate, 400 mcg offers better value at 80/100. It costs £9.70 but provides 60 capsules. This makes it a more affordable long-term option for those managing MTHFR gene variants on a budget.
Jarrow Formulas Vegan Methyl Folate, 400 mcg comes in small veggie capsules that have no smell or taste. Users often report better energy levels after a few weeks. Be careful if you are sensitive to methyl donors, as some people feel anxious or irritable when taking it. Solgar Folate (As Metafolin®) 400µg comes in tablet form and has a proven track record of raising blood folate levels in lab tests. It is a reliable way to get B9 without the conversion issues of synthetic versions.
How Do the Scores Compare?
Folate (As Metafolin®) 400µ...
Solgar
|
Vegan Methyl Folate, 400 mc...
Jarrow Formulas
|
|
|---|---|---|
| Overall Score | 86.0 | 81.0 |
| Effectiveness |
88.0/100
Best
|
85.0/100 |
| Ingredient Quality |
93.0/100
Best
|
90.0/100 |
| Value for Money | 68.0/100 |
80.0/100
Best
|
| Side Effects |
95.0/100
Best
|
77.0/100 |
| Certifications |
76.0/100
Best
|
35.0/100 |
| Best Price |
£8.05
Holland & Barrett →
Cheapest
|
£9.89 iHerb → |
| Form | Tablets | None |
| Dose | None | None |
| Third-Party Tested | ✗ No | ✗ No |
| Reviews Analysed | 58 | 50 |
Folate (As Metafolin®) 400µg 50 Tablets
Pros
- ✓Uses Metafolin® (L-5-methyltetrahydrofolate), the bioactive form directly usable by the body — superior absorption vs. synthetic folic acid
- ✓Highly effective for MTHFR mutation carriers who cannot convert regular folic acid
- ✓Multiple reviewers report confirmed improvements in blood folate levels via lab testing
- ✓Small, easy-to-swallow tablets with neutral taste and no reported digestive side effects
Cons
- ✗Small pack size — 50 tablets is only ~7 weeks' supply at the standard one-per-day dose
- ✗Not third-party tested per product specs, limiting independent purity verification
- ✗One Amazon reviewer reported receiving 46 tablets instead of 50 (possible quality control lapse)
- ✗Several iHerb reviews appear to describe the 1000mcg/120-tablet variant rather than this 400µg/50-tablet product, slightly muddying the review signal
Best For
Vegan Methyl Folate, 400 mcg, 60...
Pros
- ✓Quatrefolic® (6S)-5-MTHF bypasses MTHFR conversion issues — multiple reviewers specifically chose it for this reason
- ✓Small capsule size consistently praised; neutral taste, no smell
- ✓Energy boost and mood improvement reported by reviewers after a few weeks of regular use
- ✓Clean excipient list — vegetable-source magnesium stearate, HPMC capsule, no unnecessary fillers
Cons
- ✗Can cause anxiety or agitation in sensitive individuals — one reviewer switched to folinic acid specifically because of this
- ✗Works best paired with B12 and B6; some reviewers noted irritability when taken without a B-complex
- ✗Not universally appropriate — one reviewer's doctor advised against the methyl form due to transulfation pathway issues
- ✗No verified third-party testing per product specs
Best For
Score Breakdown: Solgar Folate Metafolin 400µg vs Jarrow Formulas Methyl Folate
Solgar's Folate as Metafolin® 400µg is a premium-grade folate supplement using L-methylfolate, the bioidentical, body-ready form of vitamin B9 that bypasses the need for hepatic conversion.
What are the key differences?
Frequently Asked Questions
Which is better, Solgar Folate Metafolin 400µg or Jarrow Formulas Methyl Folate? ▼
Is Solgar Folate Metafolin 400µg worth the price compared to Jarrow Formulas Methyl Folate? ▼
Which has fewer side effects? ▼
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Disclaimer: AIScored provides data-driven comparisons based on publicly available reviews. This is not medical advice. Affiliate links may earn us a commission at no extra cost to you.
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